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2-D08 (2',3',4'-trihydroxy flavone) is a cell permeable, mechanistically unique inhibitor of protein sumoylation. 2-D08 Chemical Structure CAS: 144707-18-6 Selleck's 2-D08 has been cited by 11 publications Cell Res,202010.1038/s41422-020-00443-z J Biol Chem,2023299 (10):105215 Nucleic Acids Res,202250 (7):3867-3891 Cell Rep,202239 (12):110994
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2-D08 is a cell permeable, mechanistically unique inhibitor of protein SUMOylation. 2-D08 also inhibits Axl with an IC50 of 0.49 nM. For research use only. We do not sell to patients. 2-D08 Chemical Structure CAS No. : 144707-18-6 or Bulk Inquiry * Please select Quantity before adding items.
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Section 2D.07: Amount of Legend: Section 2D.08: Arrows: Section 2D.09: Numbered Highway Systems: Section 2D.10: Route Signs and Auxiliary Signs: Section 2D.11: Design of Route Signs:. CHAPTER 2D. GUIDE SIGNS—CONVENTIONAL ROADS; Table 2D-1: Conventional Road Guide Sign Sizes: Table 2D-2: Recommended Minimum Letter Heights on Street Name Signs :
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903.7.8 Arrows (MUTCD Section 2D.08) Support. Arrows are used for lane assignment and to indicate the direction toward designated routes or destinations. Figure 903.7.8 shows the various standard arrow designs that have been approved for use on guide signs. Detailed drawings and standardized sizes based on ranges of letter heights for these.
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Small ubiquitin-like modifier (SUMO) binding (termed SUMOylation) emerged as the inducer for the sorting of bioactive molecules into extracellular vesicles (EVs), triggering lymphangiogenesis and further driving tumor lymph node (LN) metastasis, but the precise mechanisms remain largely unclear.